COVID-19 now ‘mutating’ less deadly – study

July 07, 2020
COVID-19

Researchers found the most dominant strain of the virus by mid-March was a mutation of the original variant called G614 not the original virus D614.

A SMALL change to a variant of the novel coronavirus has helped it better copy itself but not make it more deadly, a new study said.

Researchers found there were two strains of the virus circulating in different countries when it reached the US: the original D614 and a mutation, G614. 

This mutation is not a deadlier version of the coronavirus but it does help the virus copy itself better, which results in a higher viral load in patients. 

Dr. Erica Ollmann Saphire, a professor of at the La Jolla Institute of Immunology in California, said viruses often mutate to “escape” antibodies created by the host’s immune system.

This phenomenon of viruses making enough changes to 'drift' away from the original virus is known as antigenic drift.

Health experts said coronavirus mutates at a slower rate than several other respiratory viruses, particularly the flu.

Scientists tracked the spread of both the G and D strain of COVID-19.

They found that while both the D virus and the G virus spread widely around the world, the G strain was more dominant by mid-March. 

They analyzed the antibody samples of people who had previously been infected with COVID-19. They wanted to see if which variant would be harder to neutralize.

Results showed the new G virus was just as well neutralized - and sometimes even better - as the original D virus. 

This means the immune system doesn't need to produce more or better-acting antibodies against the G virus, despite it being better at spreading.

“These findings suggest that the newer form of the virus may be even more readily transmitted than the original form,” said senior author Dr. Bette Korber, a fellow at Los Alamos National Laboratory. “Whether or not that conclusion is ultimately confirmed, it highlights the value of what were already good ideas: to wear masks and to maintain social distancing.” 

Dr. Saphire said the virus "wants” to be transmissible, which is why many get a mild cases, or have no symptoms at all. “A virus that kills its host rapidly doesn't go as far--think of cases of Ebola,” she said.

She added that a virus that lets its host go about their business will disseminate better - like with the common cold. (DailyMail)